Liquid purification or separation – Processes – Including controlling process in response to a sensed condition
Patent
1990-05-16
1991-07-16
Jones, W. Gary
Liquid purification or separation
Processes
Including controlling process in response to a sensed condition
210781, 210782, 210514, 436177, 494 37, 422101, B01D 2126
Patent
active
050322885
ABSTRACT:
A method of use is disclosed of a device that causes phase separation of whole blood, using much lower centrifugal forces. As a result, leukocytes are separated from blood cells having specific gravities of 1.09 g/ml or higher. The method preferably uses a separation chamber arranged so that its long dimension or axis is parallel, not perpendicular, to the spin axis, and a valve that allows automatic removal of the ligher phase(s).
In one aspect, the method separates a lighter phase from a heavier phase, for example, lymphocytes from whole blood, using a centrifugal force of reduced amount. In another aspect, DNA is extracted readily from the separated lighter phase since it is less likely that the lighter phase will be contaminated by erythrocytes as occurs in conventional separation techniques.
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Atwood Susan M.
Columbus Richard L.
Freyler Deborah P.
Palmer Harvey J.
Eastman Kodak Company
Jones W. Gary
Schmidt Dana M.
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