Blood-coagulation-promoting products and methods of preparing th

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424101, A61K 3514, A61K 3516, A61K 3702, C07G 700

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active

043917461

ABSTRACT:
Blood-coagulation-promoting products substantially free of thrombin are prepared from human blood plasma by contacting a human blood plasma fraction containing coagulation Factors II, VII, IX and X with an anion exchanger to adsorb the coagulation Factors, which are subsequently eluted from the anion exchanger. The eluate is treated to generate a substance having Factor VIII Inhibitor Bypassing Activity and being substantially free of thrombin, and activated Factor X.

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