Blood-coagulation factor XIIA .beta. monoclonal antibody and imm

Details Blood-coagulation factor XIIA .beta. monoclonal antibody and imm Blood-coagulation factor XIIA .beta. monoclonal antibody and imm

1993-11-17

1996-03-19

Parr, Margaret

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 71, 435 7021, 43524027, 435975, 53038825, 53038826, 5303913, G01N 3353, G01N 3368, C12N 512, C07K 1636

Patent

active

055003494

ABSTRACT:
A monoclonal antibody which binds to Factor .beta.XII and which shows substantially no binding to Factor XII. This antibody may be used in immunoassays to measure Factor .beta.XIIa levels in blood, for example for studies of blood coagulation systems and of thrombotic disorders.

REFERENCES:
patent: 4963657 (1990-10-01), Pixley
Fujikawa, K. and McMullen, B. A. J. Biol. Chem. 258:10924-10933 (1983).
McMullen, B. A. and Fujikawa, K. J. Biol Chem 260:5328-5341 (1985).
Cool, D. E. et al J. Biol Chem 260:13666-13676 (1985).

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