Blood coagulation and separation

Liquid purification or separation – With alarm – indicator – register – recorder – signal or... – Responsive to fluid flow

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Details

210 51, 210 59, 210 83, 210209, 210DIG23, B01D 2126

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active

041893824

ABSTRACT:
Methods and apparatus for separating blood which utilize suspendable contact-activating particles to initiate blood clotting generally throughout the volume of blood are disclosed herein. The contact-activating particles are deposited in a vessel; and when whole blood is supplied to the vessel, the particles are suspended throughout the volume of the blood and remain so suspended, without mechanical agitation, during at least the initial stages of coagulation. The particles are precipitated from the serum portion of the blood during a subsequent centrifugal separation. Also, a process for making appropriately sized contact-activating particles is disclosed.

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Ratnoff et al., American Journal of Medicine, Aug. 1958, pp. 160-168, "Role of Hageman Factor in the Initiation of Clotting by Glass".
Soulier et al., Brit. J. Haemat., 1960, 6, 88, "New Data on Hageman Factor and and Plasma Thromboplastin Antecedent".

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