Blood cell volume monitoring

Details Blood cell volume monitoring Blood cell volume monitoring

1981-04-06

1983-02-22

Turk, Arnold

Chemistry: analytical and immunological testing

Biological cellular material tested

204 1T, 324 714, 356 39, 436149, G01N 2704, G01N 3350

Patent

active

043746446

ABSTRACT:
By subjecting cells, such as red blood cells, to a hypotonic solution or a solution having a lytic agent, the cells will rapidly attain a change in volume and electrical resistance parameters, which change is measured as a function of time, for example, by a Coulter Counter.RTM. particle measuring instrument. The relationship between the change in the cell resistance or cell volume and the time of immersion in the volume changing solution provides a discriminator between a normality, different diseases, and certain inherited differences.

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patent: 3606539 (1971-09-01), Polanyi et al.
patent: 4278936 (1981-07-01), Shine
Hempling, Acta Cytologica, vol. 21, No. 1, 1977, pp. 96-100.
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Haynes, Blood Cells, vol. 6, pp. 201-213, 1980.
Tatsumi et al., Poster No. 613 presented at the International Hematology Congress at Montreal, Canada, on Aug. 18-22, 1980.
Ueda et al., Poster No. 1459 presented at the International Hematology Congress at Montreal, Canada, on Aug. 18-22, 1980.

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