Surgery – Container for blood or body treating material – or means used... – Materials mixed within container
Patent
1993-09-02
1995-04-11
Green, Randall L.
Surgery
Container for blood or body treating material, or means used...
Materials mixed within container
604 56, 604 82, 604 83, 604 84, 604 85, 604 87, 604 92, 604403, 128DIG24, A61B 1900, A61M 532
Patent
active
054053439
DESCRIPTION:
BRIEF SUMMARY
The invention is directed to a blood bag system for donor blood and/or blood products comprising a bag and at least one tubing connected thereto, the system being composed of at least partly transparent plastics material.
Prior blood bag systems by means of which donor blood is collected and processed comprise a collection bag and/or one or several further bags connected thereto and interconnected by tubings. The bags are made of a flexible plastic sheet material; the tubings are likewise made of flexible plastics. The plastics materials of bags and tubings are at least partly transparent. The bags are used, on the one hand, for collecting blood or blood fractions into which the donor blood is separated by centrifuging, for instance plasma, thrombocytes and erythrocytes, and on the other hand for accommodating special washing or additive solutions.
Working with blood bags poses the particular problem that the preparation introduced into the sterile blood bag may contain viruses which need to be inactivated.
It is the objective of the invention to provide a blood bag system in which the blood or blood components from individual donors may be rendered virus-safe or may be stored in virus-safe fashion, wherein the means for rendering the blood or the blood components virus-safe are stored up to the time of use in sections of the system which are necessary for blood processing.
With a blood bag system for donor blood and/or blood products comprising a bag and at least one tubing connected thereto, the system being made of at least partly transparent plastics material, the above-specified objective is achieved in accordance with the invention in that photoactive substances (31) can be enclosed in a closed-off section of the tubing of the ready-to-use system, which can be handled individually as an independent unit.
Likewise, with a blood bag system for donor blood and/or blood products comprising bags and tubings made of at least partly transparent plastics material, in which the tubings interconnect the bags and/or are connected to other tubings, the above-specified objective is achieved in accordance with the invention in that photoactive substances can be enclosed in closed-off sections of the tubings of the ready-to-use system, which can be handled individually as an independent unit.
When photoactive substances are placed in the tubings of the blood bag systems during manufacture thereof, and when these substances are co-sterilized in the blood bag system, it is possible upon use to perform in said blood bag systems by means of said additives a treatment, especially virus inactivation of the donor blood or blood plasma, by exposing the blood bag systems to light after the donor blood has been combined with said photoactive substances. The photoactive substances exhibit the property of being stimulated by light and of emitting energy, which results in the inactivation of viruses possibly present in the preparation.
Furthermore, with a blood bag system for donor blood and/or blood products comprising at least one bag and at least one tubing connected thereto by means of which the bags may be connected otherwise, wherein the system is at least partly made of transparent plastics material, the specified objective is achieved by the feature that a blood bag system which is independent and may be handled individually and comprises a bag and a tubing which encloses photoactive substances in closed-off sections thereof, may be combined with another blood bag system which is likewise independent and to be handled individually and consists of a bag and a tubing or several bags with tubings interconnecting said bags, by interconnecting said blood bag systems.
Thus, one of the two blood bag systems may be free from photoactive substances. While virus inactivation is fully effective, it is possible to provide one of the combined systems at less expense.
The combination may be effected by coupling a tubing of one blood bag system to a tubing of the other blood bag system with the aid of a welding device under sterile co
REFERENCES:
patent: 3874384 (1975-04-01), Deindoerfer et al.
patent: 5304113 (1994-04-01), Sieber et al.
Blutspendedienst der Landesverbande des Deutschen Roten Kreuzes
Green Randall L.
Zuttarelli P.
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