Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Chemical aftertreatment – e.g. – acylation – methylation – etc.
Reexamination Certificate
2006-11-21
2006-11-21
Tsang, Cecilia J. (Department: 1654)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Chemical aftertreatment, e.g., acylation, methylation, etc.
C530S300000, C530S333000, C530S335000, C530S344000, C514S002600
Reexamination Certificate
active
07138490
ABSTRACT:
A process for purification which permits satisfactory removal of impurities from a block copolymer consisting essentially of polyethylene glycols and poly(acidic amino acid) and is suitable for the production of a polymeric carrier having a pharmaceutically acceptable purity; a process for producing such a polymeric carrier; a block copolymer reduced in impurity content; a polymeric carrier as described above; pharmaceutical preparations in polymeric form, produced by the use of the carrier; and a method of subjecting polyethylene glycols and poly(acidic amino acids)—which are impurities contained in the block copolymer—to treatment with either an ion-exchange resin or a partition/absorption resin and then determining the quantities of them with a gel filtration column.
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Nakanishi Takeshi
Shimizu Kazuhisa
Suzuki Masanobu
Uehara Ryuji
Kosar Andrew D.
Nields & Lemack
Nippon Kayaku Kabushiki Kaisha
Sakurai Yasuhisa
Tsang Cecilia J.
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