Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...
Patent
1987-07-16
1989-09-26
Bond, Robert T.
Organic compounds -- part of the class 532-570 series
Organic compounds
Unsubstituted hydrocarbyl chain between the ring and the -c-...
435121, 514183, C07D227093
Patent
active
048701726
ABSTRACT:
A novel compound having anti-tumor activity is disclosed which is 1,12-dihydroxy-1,6,12,17-tetraazacyclodocosan-2,5,13,16-tetrone produced microbiologically by culturing a microorganism belonging to the genus of Alteromonas or, in particular, Alteromonas haloplanktis SB-1123. The characterization data of the compound and the microbiological properties of the microorganism are described. The results of in vitro assays are given for the anti-tumor activity of the compound against L-1210 and IMC carcinoma cells.
REFERENCES:
patent: 4174428 (1979-11-01), Tabushi et al.
Ishizuka Masaaki
Kamayama Toshiyuki
Kurasawa Shogo
Okami Yoshiro
Takahashi Atsushi
Bond Robert T.
Microbial Chemistry Research Foundation
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