Bisphosphonic acid derivatives as anti-arthritic agents

Details Bisphosphonic acid derivatives as anti-arthritic agents Bisphosphonic acid derivatives as anti-arthritic agents

1993-02-19

1995-05-02

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus esters

562 8, 546 22, 546 23, 548112, 548113, 548128, 549 5, 549 6, C07C 6730, C07F 940, C07F 944, C07F 958

Patent

active

054121418

ABSTRACT:
The bisphosphonates of formula (III)

REFERENCES:
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patent: 4746654 (1988-05-01), Breliere et al.
Surtz, G. et al., Synthesis, "Synthesis of Novel Functionalized gem-Bisphosphonates," 661-662 (1991).
V. H. Wissman et al., Angew. Chemie 1980, 92(2), 129-130.
Helvetica Chimica Acta. vol. XLI, (1958)-No. 66, pp. 539-547.
J. Org. Chem. 1980, 45, "Photochemical Syntheses of 1,2-Diazepines. 11.1 Regiospecific Synthesis of 1,2-Dihydro-1,2-diazepin-3-ones", pp. 5095-5100.

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