Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1993-01-19
1994-12-27
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
546 24, 548112, 548118, 558158, A61K 31675, C07F 96524, C07F 96539
Patent
active
053766474
ABSTRACT:
A bisphosphonic acid derivative of the general formula (I): ##STR1## wherein A is an optionally substituted cyclic group; R.sup.1 is hydrogen atom or a lower alkanoyl group; R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are the same or different and are hydrogen atom or a lower alkyl group; m is 0, 1 or 2; and n is an integer from 2 to 10, or a salt thereof is disclosed. A process for its production and a bone resorption inhibitor containing the compound of the general formula (I) or a salt thereof are also disclosed.
REFERENCES:
patent: 4096208 (1978-06-01), Dursch et al.
patent: 4719203 (1988-01-01), Bosies et al.
patent: 4746654 (1988-05-01), Breliere et al.
patent: 5036058 (1991-07-01), Jaeggi et al.
Kawamura Noriaki
Sohda Takashi
Taketomi Shigehisa
Yamazaki Iwao
Rotman Alan L.
Takeda Chemical Industries Ltd.
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