Bisphosphonates prevent bone loss associated with immunosuppress

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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514103, 514104, 514107, 514108, A61K 3166

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active

056165714

ABSTRACT:
Bisphosphonate, particularly alendronate, can prevent or treat bone loss associated with immunosuppressive therapy, whether or not the immunosuppressive therapy is associated with an organ transplant.

REFERENCES:
patent: 4870063 (1989-09-01), Benderup et al.
Hay, J. E. Bone Disease In Liver Transplant Recipients Gastroenterology Clinics of North America vol. 22, Jun. 1993, pp. 337-349.
Fleisch, H. Bisphosphonates: A New Class of Drugs in Diseases of Bone and Calcium Metabolism Recent Results in Cancer Research, vol. 116, 1989 pp. 1-28.
Lukert, B. P. et al. Glucocorticoid-Induced Osteoporosis, Rheumatic Disease Clinic of North America vol. 20, Aug. 1994, pp. 629-650.

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