Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Structurally-modified antibody – immunoglobulin – or fragment...
Patent
1995-05-26
1998-11-10
Feisee, Lila
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Structurally-modified antibody, immunoglobulin, or fragment...
42419511, 4241801, 4241981, 5303873, 5303877, 53038822, 530399, A61K 39385, A61K 39395, C12P 2108, C07K 1646
Patent
active
058339850
ABSTRACT:
Bispecific molecules comprising a non-immunoglobulin tumor cell specific ligand and an antibody which binds the Fc receptor of an effector cell at a site that is not inhibited by endogenous immunoglobulin are disclosed. The bispecific molecules can be used to induce a specific antibody dependent effector cell-mediated cytotoxicity against tumor cells, such as small cell lung carcinoma (SCLC) cells, either in vivo or in vitro.
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Ball Edward D.
Fanger Michael W.
Bansal Geetha P.
Feisee Lila
Medarex Inc.
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