Bisamidine derivatives of 5,10-dioxo-4,5,9,10-tetrahydro-4,9-dio

Details Bisamidine derivatives of 5,10-dioxo-4,5,9,10-tetrahydro-4,9-dio Bisamidine derivatives of 5,10-dioxo-4,5,9,10-tetrahydro-4,9-dio

1984-02-15

1986-07-08

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

544296, 544333, 544361, 546109, 546110, 546187, 546203, 546204, 548518, 549277, 549278, C07D41300, C07D40300, C07D49306

Patent

active

045994099

ABSTRACT:
The present invention relates to new bisamidine derivatives of polycyclic compounds such as 5,10-dioxo-4,5,9,10-tetrahydro-4,9-dioxapyrene-6(5H)-phenanthridone and 5,10-dioxo-4,5,9,10-tetrahydro-4,9-dioxapyrenephenanthridine and to a process for their preparation. The polycyclic bisamidines according to the invention are distinguished by valuable chemotherapeutic properties, such as, for example, an action against amoebas and trichomonads.

REFERENCES:
patent: 2303517 (1942-12-01), Walls et al.
patent: 2495051 (1950-01-01), Barbar
patent: 3122553 (1964-02-01), Seneca
patent: 3838131 (1974-09-01), Gauthier
patent: 3953455 (1976-04-01), Meyer et al.
Chemical Abstracts, vol. 91, No. 17, (1979), 140744z.

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