Bis-transition-metal-chelate probes

Details Bis-transition-metal-chelate probes Bis-transition-metal-chelate probes

2008-05-13

2008-05-13

Solola, Taofiq (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S338000, C544S064000

Reexamination Certificate

active

07371745

ABSTRACT:
A molecule for labeling a target material is provided including two transition-metal chelates and a detectable group. The molecule has the general structural formula (I):wherein: (a) Y and Y′ are each a transition metal, (b) R1and R1′are each independently CH(COO−), CH(COOH), or absent; (c) R2and R2′are linkers each having a length of from about 3.0 to about 20 Å; and (d) X is a detectable group. The linkers may be linear or branched, may contain aromatic moieties, and may optionally be further substituted. Methods of using the molecules of the invention as probes in detecting and analyzing target materials as well as kits including the molecule of the invention are also provided.

REFERENCES:
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