Bis-thioalkylfurans useful as cyclopentenone prostaglandin inter

Details Bis-thioalkylfurans useful as cyclopentenone prostaglandin inter Bis-thioalkylfurans useful as cyclopentenone prostaglandin inter

1982-02-02

1983-06-28

Chan, Nicky

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549502, 549483, 549453, 549449, 549414, 549 21, 568361, 568379, C07D30906, C07D30740

Patent

active

043907075

ABSTRACT:
A method for the preparation of cyclopentenones of the general formula (VIII): ##STR1## wherein n is 5-7, has been developed which proceeds via the acid catalyzed deprotection and rearrangement of novel substituted-.alpha.-hydroxymethylfurans of general formula (VII): ##STR2## wherein R is a hydroxyl protecting group, R.sub.1 and R.sub.2 are methyl or ethyl or together form --(CH.sub.2).sub.3 -- and n is as above described. Cyclopentenones of formula VIII are useful intermediates in prostaglandin analog synthesis.

REFERENCES:
patent: 4254285 (1980-11-01), Wissner
B. T. Grobel and D. Seebach, Synthesis, 6, 357 (1977).

Affiliated with

Also associated with

Rating

Bis-thioalkylfurans useful as cyclopentenone prostaglandin inter does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Bis-thioalkylfurans useful as cyclopentenone prostaglandin inter, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bis-thioalkylfurans useful as cyclopentenone prostaglandin inter will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-934713