Bis(substituted methyl)-methyl-isoquinoline derivatives and phar

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546146, 546147, 546149, 546150, A61K 3147, C07D21716

Patent

active

046543511

ABSTRACT:
The invention relates to new bis(substituted methyl)-methyl-isoquinoline derivatives of the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 represent hydroxyl or alkoxy having from 1 to 6 carbon atoms,

REFERENCES:
patent: 3562280 (1971-02-01), Leimgruber et al.
patent: 4373104 (1983-02-01), Takacs et al.
Chem. Ber. 102, 915 (1969).
G. Bernath, K. Kovacs, K. L. Lang: Acta Chim. Sci. Hung. 65, 347 (1970).
Swinyard et al.: J. Pharmacol. Exp. Ther. 106, 319 (1952).
Niemegeers, C. J. E., et al.: Arzneimittel Forsch. 25:15/9 (1975).

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