Bis-S-alkylbenzene derivatives

Details Bis-S-alkylbenzene derivatives Bis-S-alkylbenzene derivatives

1988-12-06

1990-06-12

Shen, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

514490, 514506, 514507, 514576, 514717, 514718, 514731, 514252, 514826, 558197, 560 32, 560135, 560138, 560142, 544396, A61K 3342, A61K 31495, C07C12506, C07D29508

Patent

active

049333291

ABSTRACT:
Novel bis-S-alkylbenzene derivatives capable of inhibiting lipoxygenase, inparticular, 5-lipoxygenase are disclosed. It is expected that the compounds, which are hardly metabolized in vivo, are highly useful in the treatment and/or prevention of various diseases, including allergic diseases such as asthma, inflammation, myocardial infarction, nephritis, scabies and gout.

REFERENCES:
patent: 4533753 (1985-08-01), McKinnie et al.
patent: 4547593 (1985-10-01), Ranken
patent: 4602113 (1986-07-01), McKinnie et al.
Beck et al, CA 88-190279l(1978).
Kompis et al, CA 91-107996k(1979).
Ranken et al, CA 100-191485c(1984).
McKinnie et al, CA 102-28149d(1985).
Ranken, CA 104-168109g(1986).
Saa et al, CA 109-189942s(1988).
Singh et al, CA 109-230716m(1988).
Saa et al, J. Org. Chem 1988 53, 4263-4273.
Y. Koshihara et al., "Caffeic Acid is a Selective . . . Biosynthesis", Biochimica et Biophysics Acta, 792 (1984) 92-97.

Affiliated with

Also associated with

Rating

Bis-S-alkylbenzene derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Bis-S-alkylbenzene derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bis-S-alkylbenzene derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-617301