Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-08-09
1997-04-01
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546 98, 546 99, 546 76, C07D22114, C07D40112, C07D22118, A61K 31445
Patent
active
056165897
ABSTRACT:
Disclosed herein are compounds pharmaceutical compositions containing same of the formula
1. A compound of the Formula ##STR1## wherein X, X', X" and X'", A, B, D, R, and R' are as identified in the specification and their preparation. Pharmaceutical compositions containing same can be used in the treatment of cancer.
REFERENCES:
patent: 4874863 (1989-10-01), Brana
patent: 5086059 (1992-02-01), Ardecky
Bousquet et al., Cancer Research, vol. 55, mar. 1, 1995, pp. 1176-1180, "Preclinical evaluation of LU 79553: A Novel Bis-naphthalimide with potent Antitumor Activity".
Berlanga Jose M.C.
Bousquet Peter
Bra na Miguel F.
de Vega Maria J.P.
Keilhauer Gerhard
BASF - Aktiengesellschaft
Berch Mark L.
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