Bis mono-and bicyclic aryl and heteroaryl compounds which inhibi

Details Bis mono-and bicyclic aryl and heteroaryl compounds which inhibi Bis mono-and bicyclic aryl and heteroaryl compounds which inhibi

1997-06-25

2000-05-02

Lambkin, Deborah C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514248, A61K 31495

Patent

active

060573201

ABSTRACT:
This invention relates to bis mono- and/or bicyclic aryl and/or heteroaryl compounds exhibiting protein tyrosine kinase inhibition activity. More specifically, it relates to the method of inhibiting abnormal cell proliferation in a patient suffering from a disorder characterized by such proliferation comprising the administration thereto of an EGF and/or PDGF receptor inhibiting effective amount of said bis mono- and/or bicyclic aryl and/or heteroaryl compound and to the preparation of said compounds and their use in pharmaceutical compositions used in this method.

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Cronin et al, "Hypotensive and bronchodilatory quinolines, isoquinolines, and quinazolines", CA 70:68419u, 1969.

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