Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-02-08
1997-08-12
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514313, 514314, 546157, 546159, 546167, A61K 3147, C07D40104, C07D40106, C07D40112
Patent
active
056566433
ABSTRACT:
This invention relates to bis mono- and/or bicyclic aryl and/or heteroaryl compounds exhibiting protein tyrosine kinase inhibition activity. More specifically, it relates to the method of inhibiting abnormal cell proliferation in a patient suffering from a disorder characterized by such proliferation comprising the administration thereto of an EGF and/or PDGF receptor inhibiting effective amount of said bis mono- and/or bicyclic aryl and/or heteroaryl compound and to the preparation of said compounds and their use in pharmaceutical compositions used in this method.
REFERENCES:
Carter et al., Chemotherapy Of Cancer, 2nd ED, John Wiley & Sons, N.Y., N.Y. (1981) pp. 362-365.
Maguire Martin P.
Myers Michael R.
Persons Paul E.
Spada Alfred P.
Nicholson James A.
Parker III Raymond S.
Raymond Richard L.
Rhone-Poulenc Rorer Pharmaceuticals Inc.
Savitzky Martin F.
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