Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1993-12-10
1996-01-02
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142348, 544353, 544354, 544356, A61K 31495, A61K 31535, C07D24152, C07D24154
Patent
active
054808839
ABSTRACT:
This invention relates to bis mono- and/or bicyclic aryl and/or heteroaryl compounds exhibiting protein tyrosine kinase inhibition activity. More specifically, it relates to the method of inhibiting abnormal cell proliferation in a patient suffering from a disorder characterized by such proliferation comprising the administration thereto of an EGF and/or PDGF receptor inhibiting effective amount of said bis mono- and/or bicyclic aryl and/or heteroaryl compound and to the preparation of said compounds and their use in pharmaceutical compositions used in this method.
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Maguire Martin P.
Myers Michael R.
Persons Paul E.
Spada Alfred P.
Cebulak Mary C.
Nicholson James A.
Parker III Raymond S.
Raymond Richard L.
Rhone-Poulenc Rorer Pharmaceuticals Inc.
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