Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1976-04-20
1977-12-13
Trousof, Natalie
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
548301, 548316, 548318, 548336, 548339, 548342, 548358, 548362, 548364, 548374, 548377, 548378, 424273P, A61K 31415, C07D23364
Patent
active
040629678
ABSTRACT:
The compounds are C.sub.2 -C.sub.8 straight chain alkanes terminally substituted, symmetrically or unsymmetrically, by N-(N'-substituted guanidino), N-(N',N"-disubstituted guanidino), N-(N'-substituted thioureido), N-(nitromethylene amidino) or S-(N-substituted isothioureido)groups. Two compounds of the invention are 1,3-bis[N'-(2-(5-methyl-4-imidazolylmethylthio)ethyl)guanidino]propane and 1,3-bis-[S-(N-2-(5-methyl-4-imidazolylmethylthio)ethyl)isothioureido]propa ne. The compounds of this invention are inhibitors of H-2 histamine receptors.
REFERENCES:
patent: 3932443 (1976-01-01), White
Brown et al., Chem. Abst. 1973, vol. 78, No. 42874d.
Durant Graham John
Ganellin Charon Robin
Edgerton William H.
Foggio Richard D.
Keps Joan S.
Smith Kline & French Laboratories Limited
Trousof Natalie
LandOfFree
Bis-guanidino-alkane compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Bis-guanidino-alkane compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bis-guanidino-alkane compounds will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-489528