Bis-biguanide antiplaque dentifrice exhibiting reduced staining

Details Bis-biguanide antiplaque dentifrice exhibiting reduced staining Bis-biguanide antiplaque dentifrice exhibiting reduced staining

1998-03-12

1999-09-28

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Ammonia, amine, or derivative thereof

424 49, 424 52, A61K 716, A61K 718, A61K 722

Patent

active

059583819

ABSTRACT:
A dual component chlorhexidine dentifrice composition in which the first component contains a bis-biguanide antibacterial agent and the second component contains an abrasive incompatible with the bis-biguanide, wherein maximum antibacterial effect on dental tissue with reduced staining is achieved when the components and are physically separated prior to use and are mixed upon application to dental tissue.

REFERENCES:
patent: 4487757 (1984-12-01), Kiozpeoplou
patent: 4565692 (1986-01-01), Mulvey et al.
patent: 5052590 (1991-10-01), Ratcliff
patent: 5766574 (1998-06-01), Christina-Beck et al.
patent: 5776437 (1998-07-01), Burgess et al.
patent: 5811080 (1998-09-01), Burgess et al.
patent: 5820852 (1998-10-01), Burgess et al.
patent: 5820853 (1998-10-01), Glandorf
patent: 5820854 (1998-10-01), Glandorf
patent: 5849269 (1998-12-01), Burgess et al.

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