Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1984-11-20
1987-09-08
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544357, A61K 31495, C07D40312
Patent
active
046924485
ABSTRACT:
Disclosed are novel bis(arylpiperazinyl)sulfur compounds represented by formula I ##STR1## wherein: R.sub.1 and R.sub.2 are each independently hydrogen, lower alkyl, halogen, nitrile or methylthio; m and n are each independently 2 or 3; and X is a dithio, thio, sulfinyl or sulfonyl and nontoxic, pharmaceutically acceptable addition salts thereof. These compounds can be used for the prevention of allergic disorders, such as asthma, rhinitis, conjunctivitis, hay fever, urticaria, food allergies, and the like.
REFERENCES:
patent: 2948727 (1960-08-01), D'Amico
patent: 3138597 (1964-06-01), Schut
Nakanishi et al., Chemical Abstracts, vol. 70, (1969), Entry 1172F.
Devlin John P.
Hargrave Karl D.
Boehringer Ingelheim Pharmaceuticals Inc.
Daus Donald G.
Frankhouser David E.
Stempel Alan R.
Teoli, Jr. William A.
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