Bis-aryl sulfonamides

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

Reexamination Certificate

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C564S085000, C564S087000, C564S088000, C514S183000, C514S210010, C514S212010, C514S317000, C514S408000, C514S562000, C514S602000

Reexamination Certificate

active

10848836

ABSTRACT:
Compounds are provided that act as potent antagonists of chemokine receptors. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of chemokine receptor-mediated diseases, and as controls in assays for the identification of chemokine antagonists.

REFERENCES:
patent: 2997368 (1961-08-01), Barent et al.
patent: 3121103 (1964-02-01), Keller et al.
patent: 3344183 (1967-09-01), Reeder et al.
patent: 3442946 (1969-05-01), Keller et al.
patent: 3534062 (1970-10-01), Wright et al.
patent: 4166452 (1979-09-01), Generales, Jr.
patent: 4256108 (1981-03-01), Theeuwes
patent: 4265874 (1981-05-01), Bonsen et al.
patent: 4372975 (1983-02-01), Mouzin et al.
patent: 4954518 (1990-09-01), Takano et al.
patent: 4992091 (1991-02-01), Vinogradoff et al.
patent: 4997940 (1991-03-01), Vinogradoff et al.
patent: 5021591 (1991-06-01), Vinogradoff et al.
patent: 5071468 (1991-12-01), Astles et al.
patent: 5093364 (1992-03-01), Richards et al.
patent: 5155121 (1992-10-01), Niewohner
patent: 5163995 (1992-11-01), Van Heertum et al.
patent: 5185348 (1993-02-01), Niewohner et al.
patent: 5217521 (1993-06-01), Durr
patent: 5338755 (1994-08-01), Wagnon et al.
patent: 5481005 (1996-01-01), Wagnon et al.
patent: 5541186 (1996-07-01), Breu et al.
patent: 5571775 (1996-11-01), Van Heertum
patent: 5589478 (1996-12-01), Yamada et al.
patent: 5780488 (1998-07-01), Bergman et al.
patent: 5973148 (1999-10-01), Ringer et al.
patent: 6136971 (2000-10-01), Harrington et al.
patent: 6200995 (2001-03-01), De la Brouse-Elwood
patent: 6297195 (2001-10-01), Gesing et al.
patent: 6297239 (2001-10-01), deSolms et al.
patent: 6316450 (2001-11-01), Bromidge et al.
patent: 6403607 (2002-06-01), Hidaka et al.
patent: 6432624 (2002-08-01), Kikuchi et al.
patent: 6653332 (2003-11-01), Jaen et al.
patent: 2002/0009116 (2002-01-01), Kobayashi et al.
patent: 2002/0012680 (2002-01-01), Patel
patent: 2002/0013314 (2002-01-01), Zhu et al.
patent: 2002/0037905 (2002-03-01), Dahl
patent: 2002/0037928 (2002-03-01), Jaen et al.
patent: 2002/0065303 (2002-05-01), Zhu et al.
patent: 2002/0072530 (2002-06-01), Zhu et al.
patent: 2002/0103202 (2002-08-01), Pinto
patent: 2003/0060460 (2003-03-01), Ohuchida et al.
patent: 2003/0139390 (2003-07-01), McGee et al.
patent: 561703 (1975-05-01), None
patent: 3544409 (1986-10-01), None
patent: 3825041 (1990-02-01), None
patent: 0 015 214 (1980-09-01), None
patent: 0 526 348 (1993-02-01), None
patent: 556673 (1993-02-01), None
patent: 0 613 894 (1994-09-01), None
patent: 884847 (1961-12-01), None
patent: 1332697 (1973-10-01), None
patent: WO 93/03013 (1993-02-01), None
patent: WO 94/20142 (1994-09-01), None
patent: WO 95/33462 (1995-12-01), None
patent: WO 96/08483 (1996-03-01), None
patent: WO 97/28129 (1997-08-01), None
patent: WO 98/11218 (1998-03-01), None
patent: WO 98/28270 (1998-07-01), None
patent: WO 98/50029 (1998-11-01), None
patent: WO 99/17777 (1999-04-01), None
patent: WO 99/32433 (1999-07-01), None
patent: WO 99/38845 (1999-08-01), None
patent: WO 99/42465 (1999-08-01), None
patent: WO 99/55324 (1999-11-01), None
patent: WO 99/55663 (1999-11-01), None
patent: WO 00/05214 (2000-02-01), None
patent: WO 00/62778 (2000-10-01), None
patent: WO 01/00579 (2001-01-01), None
patent: WO 01/09097 (2001-02-01), None
patent: WO 01/17971 (2001-03-01), None
patent: WO 01/19788 (2001-03-01), None
patent: WO 01/19798 (2001-03-01), None
patent: WO 01/32646 (2001-05-01), None
patent: WO 01/56607 (2001-08-01), None
patent: WO 01/56989 (2001-08-01), None
patent: WO 01/57003 (2001-08-01), None
patent: WO 01/57020 (2001-08-01), None
patent: WO 01/60319 (2001-08-01), None
patent: WO 02/00633 (2002-01-01), None
patent: WO 02/18326 (2002-03-01), None
patent: WO 02/30358 (2002-04-01), None
patent: WO 02/54867 (2002-07-01), None
patent: WO 02/55501 (2002-07-01), None
patent: WO 02/59080 (2002-08-01), None
patent: WO 03/99773 (2003-12-01), None
patent: WO 2005/004810 (2005-01-01), None
Berman et al., Immunol.Invest17, pp. 625-677, 1988.
Campbell, et al.,J. Exp. Med., 195(1), pp. 135-141, 2002.
Dahinden, et al.,J. Exp. Med., 179, pp. 751-756, 1994.
Dannhardt, et al., 37Eur.J.Med.Chem., pp. 147-161, 2002.
Davidson et al.,J Exp Med., 184, pp. 241-251; 1996.
Kavanaugh et al.,J. Immunol., 146, pp. 4149-4156, 1991.
Kontoyiannis et al.,Immunity, 10, pp. 387-398, 1999.
Kosiewicz et al.,J. Clin Invest., 107(6), pp. 695-702, 2001.
Kunkel, et al.,J. Exp. Med.192(5), pp. 761-767, 2000.
Lothrop et al.,J.Amer.Chem.Coc., Coden:Jacsat, 63, pp. 2564-2567, 1941.
Murphy,Rev. Immun., 12, pp. 593-633, 1994.
Neote, et al.,Cell, 72, pp. 415-425, 1993.
Panwala, et al.,J Immunol., 161, pp. 5733-5744, 1998.
Papadakis, et al.,J. Immunol., 165, pp. 5069-5076, 2000.
Powrie et al.,Int Immunol., 5(11), pp. 1461-1471, 1993.
Qiuping Z et al.,Cancer Res., 63, pp. 6469-6477, 2003.
Schaarschmidt; Herzenberg, ChemBer., Coden:Chbeam, 53, pp. 1388-1399, 1920.
Schall,Cytokine, 3, pp. 165-183, 1991.
Schall, et al.,Curr. Opin. Immunol., 6, pp. 865-873, 1994.
SciFinder Search Results (Feb. 19, 2004).
SciFinder Search Results (Feb. 20, 2004).
Silvestri et al.,Medicinal Chemistry Research, 11(4), pp. 195-218, 2002.
Street et al., Journal of Chemical Research, Synopses, (5), pp. 154-155, 1987.
Targan et al.,N Engl J Med., 337(15), pp. 1029-1035, 1997.
Uehara, et al.,J. Immunol, 168(6), pp. 2811-2819, 2002.
Ullmann; Bleier, Chem. Ber., Coden:Chbeam, 35, pp. 4273-4280, 1902.
Van Riper, et al.,J. Exp. Med., 177, pp. 851-856, 1993.
Wurbel, et al.,Blood, 98(9), pp. 2626-2632, 2001.
Youn BS, et al., Apoptosis, 7, pp. 271-276, 2002.
Zaballos, et al.,J. Immunol., 162, pp. 5671-5675, 1999.
Science IP Search Report (Mar. 1, 2005).
Search Report (Sep. 3, 2002).
Wu et al., Yingyong Huaxue (1995) 12(4) 80-3.
Sannicolo, Chem Abst. 106:175880 (1987).
Yavorskii et al., Chem. Abst. 103:160483 (1985).
Hellwinkel et al., Chem Abst. 100:5549 (1984).
Fryer et al., Chem Abst. 97:72335 (1982).
Field et al., Chem. Abst. 80:37186 (1974).
Kametani et al., Chem Abst 73:77127 (1970).
MacDonald et al., Chem Abst. 71:61183 (1969).
Reeder et al., Chem. Abst. 70:37850 (1969).
Hromatka et al., Chem Abst 69:19132 (1968).

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