Bis-(amidine phenyl)cyclohexanecarboxylic acid ketones, composit

Details Bis-(amidine phenyl)cyclohexanecarboxylic acid ketones, composit Bis-(amidine phenyl)cyclohexanecarboxylic acid ketones, composit

1981-06-05

1982-07-27

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

562440, C07C12300, A61K 31195

Patent

active

043417973

ABSTRACT:
Bis-(amidine phenyl)cyclohexanecarboxylic acid ketones are provided having the structure ##STR1## wherein R is hydrogen, lower alkyl or aryl and n is 0, 1 or 2, and acid-addition salts thereof. In addition, pharmaceutical compositions containing the above compounds and a method of using same to treat inflammatory conditions in mammalian species are also provided.

REFERENCES:
"Synthese von .alpha.,.alpha.'-Bis-[amidinobenzyliden]-und .alpha.,.alpha.'-Bis-[amidinobenzyl]-cycloalkanonen," Wagner et al, Pharmazie 32, pp. 141-145, (1977).

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