Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-02-10
1997-08-05
Gerstl, Robert
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548138, C07D26114, A61K 3141
Patent
active
056543220
ABSTRACT:
This invention relates to a biphenylmethane derivative represented by the formula (1): ##STR1## wherein A represents a group ##STR2## in which R.sup.1, X, Y, Z and B are as defined in the Specification. The compounds have potent angiotensin II antagonist activity and anti-hypertensive effect. They have therapeutic utility for circulatory diseases such as hypertension, heart diseases and cerebral apoplexy.
REFERENCES:
patent: 5389660 (1995-02-01), Greenlee
patent: 5434167 (1995-07-01), Ferrari
Amano Hirotaka
Hirata Terukage
Nomiyama Jun
Okuhira Masayasu
Sakae Nobuya
Gerstl Robert
Wakunaga Seiyaku Kabushiki Kaisha
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