Biphenyldiphosphine compounds

Details Biphenyldiphosphine compounds Biphenyldiphosphine compounds

2006-08-22

2006-08-22

Lorengo, J. A. (Department: 1755)

Catalyst, solid sorbent, or support therefor: product or process

Catalyst or precursor therefor

Organic compound containing

C502S102000, C502S104000, C502S152000, C502S155000, C502S162000, C556S013000, C556S019000, C549S270000

Reexamination Certificate

active

07094725

ABSTRACT:
The present invention provides compounds of the formulawhereinR is optionally substituted lower alkyl, cycloalkyl or aryl;R′ is alkyl or aryl;n is zero or an integer of 1 or 2;or an enantiomer thereof; or an enantiomeric mixture thereof.The compounds of formula (I) are bridged C2-symmetric biphenyldiphosphine analogs and, thus, may be employed as ligands to generate chiral transition metal catalysts which may be applied in a variety of asymmetric reactions. The compounds of the present invention are easily accessible in high diastereomeric and optical purity according to the methods disclosed herein.

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