Biphenyl-tetrazole intermediate compounds

Details Biphenyl-tetrazole intermediate compounds Biphenyl-tetrazole intermediate compounds

1994-01-31

1995-05-30

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546276, 544328, 544331, C07D25704, C07D21376, C07D23922

Patent

active

054202922

ABSTRACT:
The invention provides a novel chemical process for the manufacture of quinoline, pyridine and imidazole derivatives of the formula IV wherein Q, Y.sup.1 and Y.sup.2 have the various meanings defined herein, and their non-toxic salts, which are angiotensin II inhibitors. The process involves the removal of an electron-deficient phenyl group or a pyridyl or pyrimidyl group from a compound of the formula VI as defined herein. Certain of the intermediates are novel and are provided as a further feature of the invention.

REFERENCES:
patent: 5252753 (1993-10-01), Russell et al.
patent: 5294716 (1994-03-01), Thomas et al.
K. Kamala, et al., Bull. Chem. Soc. JPN. (1988) 61, No. 10, 3791-3793: "Synthesis of 2-Aryl[1,2,4]triazolo[1,5-a]pyrimidines.".
P. G. Houghton, et al., J. Chem. Soc. Perkin Trans I (1985), 1471-1479: "Intramolecular Reaction Between Nitro and Carbodi-imide Groups; A New Synthesis of 2-Arylbenzotriazoles.".
Bianchetti, "Distacco per Idrazinolisi . . . ", Gazz. Chim. Ital., vol. 94, p. 340, 1968, English abstract only.

Affiliated with

Also associated with

Rating

Biphenyl-tetrazole intermediate compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Biphenyl-tetrazole intermediate compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biphenyl-tetrazole intermediate compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-363262