Biphenyl oxadiazinone angiotensin II inhibitors

Details Biphenyl oxadiazinone angiotensin II inhibitors Biphenyl oxadiazinone angiotensin II inhibitors

1991-12-20

1993-07-06

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544 68, A61K 31535, C07D27304

Patent

active

052254089

ABSTRACT:
Angiotension II inhibition is exhibited by ##STR1## wherein: R.sup.1 and R.sup.2 are each independently hydrogen, alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl, thiophenalkyl, pyridylalkyl, or --R.sup.8 CO.sub.2 R.sup.9 ;

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patent: 5064825 (1991-11-01), Chakravarty et al.
Chiu et al., European Journal of Pharmacology, 157 (1988) pp. 13-21.

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