Biphenyl derivatives, process for preparing the same and interme

Details Biphenyl derivatives, process for preparing the same and interme Biphenyl derivatives, process for preparing the same and interme

1990-05-29

1992-04-07

Chan, Nicky

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549362, 549435, 549436, C07D31918, C07D32110, C07D31764

Patent

active

051030233

ABSTRACT:
Novel biphenyl derivatives of the formula: wherein R.sup.1 is a substituted or unsubstituted aminocarbonyl group, aminothiocarbonyl group, a substituted or unsubstituted lower alkoxycarbonyl group, cyano group, or a group of the formula: ##STR1## one or two of R.sup.2 to R.sup.7 are hydrogen atom, and the remaining groups are the same or different and are each a lower alkoxy group, a phenyl(lower)alkoxy group or hydroxy group, or the adjacent two groups thereof combine to form a lower alkylenedioxy group, and Alk.sup.1 is a lower alkylene group, or a pharmaceutically acceptable salt thereof, which are useful for the prophylaxis and treatment of hepatic diseases, and processes for preparing the same, and intermediates therefor.

REFERENCES:
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patent: 4904694 (1990-02-01), Matsuoka et al.
Wunsche, C. et al., "Elektronenstoss-Induzierte Alkyl-Und Wasserstoffwanderungen Bei Diphensaurederivaten", Tetrahedron, vol. 24, No. 8, Apr. 1968, pp. 3407-3416.
Zhang, Honglian et al, "Syntheses of Some Derivatives of Schizandrins", Yaoxue Xuebao 1981, 16(12), 914-19.
Chemical Abstracts, vol. 96, No. 23, 7th Jun. 1982, p. 630, No. 1992255x.
Dallacker, Franz et al, "Preparation and Electrophilic Substitution of Phenanthro[3,4-d:5,6-d']bis(1,3-dioxole)", Chem.-Ztg. 1984, 108(10), 329-31.
Chemical Abstracts, vol. 102, No. 13, Apr. 1, 1985, p. 700, No. 113343g.

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