Biphenyl derivatives, pharmaceutical compositions containing the

Details Biphenyl derivatives, pharmaceutical compositions containing the Biphenyl derivatives, pharmaceutical compositions containing the

1996-08-01

1998-04-07

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514255, 5142778, 514326, 514331, 514381, 514423, 514428, 514539, 514562, 514563, 514620, 544129, 544130, 544 586, 544366, 546210, 546226, 546230, 546231, 548252, 548539, 548569, 560 12, 560 13, 560 16, 560 21, 560 34, 560 35, 562426, 562439, 562430, 562440, 564163, 564164, A61K 31445, A61K 3140, A61K 31495, C07D21106, C07D295385

Patent

active

057365598

ABSTRACT:
The invention relates to biphenyl derivatives of general formula ##STR1## wherein A to E and X are defined as in claim 1, the stereoisomers thereof, including their mixtures and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable properties, preferably aggregation-inhibiting effects, pharmaceutical compositions containing these compounds and processes for preparing them.

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patent: 3821268 (1974-06-01), Diamond
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patent: 4661522 (1987-04-01), Beetz
patent: 4746737 (1988-05-01), Fujii
patent: 5061693 (1991-10-01), Nutt
patent: 5084466 (1992-01-01), Alig
Marder VJ & Sherry S. The New England Journal of Medicine, 318 (23), pp. 1512-1520, Jun. 1988.
Frearson PM & Stern ES. J. Chem. Soc., pp. 3062-3064 (CA53:3219f), 1959.

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