Biphenyl compounds useful as muscarinic receptor antagonists

Details Biphenyl compounds useful as muscarinic receptor antagonists Biphenyl compounds useful as muscarinic receptor antagonists

2007-07-19

2009-02-17

Andres, Janet L. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S208000

Reexamination Certificate

active

07491736

ABSTRACT:
This invention provides compounds of formula I:wherein a, b, c, d, m, n, p, s, t, W, Ar1, R1, R2, R3, R4, R6, R7, and R8are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.

REFERENCES:
patent: 6617325 (2003-09-01), Lehmann-Lintz et al.
patent: 6635764 (2003-10-01), Mammen et al.
patent: 6656694 (2003-12-01), Mammen
patent: 6693202 (2004-02-01), Aggen et al.
patent: 2003/0018019 (2003-01-01), Meade et al.
patent: 2004/0167167 (2004-08-01), Mammen et al.
patent: 2004/0209860 (2004-10-01), Mammen et al.
patent: 2004/0209915 (2004-10-01), Mammen et al.
patent: 2005/0113417 (2005-05-01), Mammen et al.
patent: 2005/0203083 (2005-09-01), Mammen et al.
patent: 2005/0203131 (2005-09-01), Mammen et al.
patent: 2005/0203132 (2005-09-01), Mammen et al.
patent: 2005/0203133 (2005-09-01), Mammen et al.
patent: 2005/0203134 (2005-09-01), Mammen et al.
patent: 2005/0203137 (2005-09-01), Mammen e al.
patent: 2005/0203138 (2005-09-01), Mammen et al.
patent: 2005/0203139 (2005-09-01), Mammen et al.
patent: 2006/0205775 (2006-09-01), Ji et al.
patent: 2006/0205784 (2006-09-01), Mu et al.
patent: 2006/0205946 (2006-09-01), Ji et al.
patent: 2007/0293461 (2007-12-01), Mammen et al.
patent: 0 747 355 (1996-12-01), None
patent: WO 95/06635 (1995-03-01), None
patent: WO 99/64043 (1999-12-01), None
patent: WO 01/42212 (2001-06-01), None
patent: WO 02/051841 (2002-07-01), None
patent: WO 2004/012684 (2004-02-01), None
Broadley et al., “Muscarinic Receptor Agonists and Antagonists”, Molecules, 6, pp. 142-193 (2001).
Eglen et al., “Muscarinic Receptor Subtypes:Pharmacology and Therapeutic Potential”, DN&P, 10(8), pp. 462-469 (1997).
Zlotos et al., “Muscarinic receptor agonists and antagonists”, Exp. Opin. Ther. Patents, 9(8), pp. 1029-1053 (1999).
Naito et al., “Selective Muscarinic Antagonist. II.1)Synthesis and Antimuscarinic Properties of Biphenylylcarbamate Derivatives”, Chem. Pharm. Bull., vol. 46, No. 8, pp. 1286-1294 (1998).
Ziedalski et at., “Advances in the Management of Chronic Obstructive Pulmonary Disease”, Expert Opin,. Pharmacother. 4(7):1063-1082 (2003).

Affiliated with

Also associated with

Rating

Biphenyl compounds useful as muscarinic receptor antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Biphenyl compounds useful as muscarinic receptor antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biphenyl compounds useful as muscarinic receptor antagonists will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4084317