Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2009-03-12
2010-12-28
Desai, Rita J (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C546S152000, C514S307000, C514S311000
Reexamination Certificate
active
07858792
ABSTRACT:
This invention provides compounds of formula I:wherein a, b, c, m, p, r, R1, R2, R3, R4, R5, R6, W and X1are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.
REFERENCES:
patent: 6617325 (2003-09-01), Lehmann-Lintz et al.
patent: 6635764 (2003-10-01), Mammen et al.
patent: 6656694 (2003-12-01), Mammen
patent: 6693202 (2004-02-01), Aggen et al.
patent: 7141671 (2006-11-01), Mammen et al.
patent: 7262205 (2007-08-01), Mammen et al.
patent: 7265133 (2007-09-01), Mammen et al.
patent: 7288657 (2007-10-01), Mammen et al.
patent: 7345060 (2008-03-01), Mammen et al.
patent: 7456199 (2008-11-01), Mammen et al.
patent: 7479562 (2009-01-01), Ji et al.
patent: 7501442 (2009-03-01), Mammen et al.
patent: 7642355 (2010-01-01), Mu et al.
patent: 2003/0018019 (2003-01-01), Meade et al.
patent: 2004/0209860 (2004-10-01), Mammen et al.
patent: 2004/0209915 (2004-10-01), Mammen et al.
patent: 2005/0203132 (2005-09-01), Mammen et al.
patent: 2005/0203134 (2005-09-01), Mammen et al.
patent: 2005/0203137 (2005-09-01), Mammen et al.
patent: 2006/0205777 (2006-09-01), Mu et al.
patent: 2006/0205778 (2006-09-01), Mu et al.
patent: 2006/0205779 (2006-09-01), Mu et al.
patent: 2007/0265310 (2007-11-01), Mammen et al.
patent: 0 747 355 (1996-12-01), None
patent: WO 95/06635 (1995-03-01), None
patent: WO 99/64043 (1999-12-01), None
patent: WO 01/42212 (2001-06-01), None
patent: WO 02/051841 (2002-07-01), None
patent: WO 2004/012684 (2004-02-01), None
U.S. Appl. No. 12/265,091, Ji et al.
U.S. Appl. No. 12/286,914, Mammen et al.
Broadley et al., “Muscarinic Receptor Agonists and Antagonists”, Molecules, 6, pp. 142-193 (2001).
Dorwald F. A., Side Reactions in Organic Synthesis, 2005, Wiley: VCH, Weinheim p. IX of Preface.
Eglen et al., “Muscarinic Receptor Subtypes:Pharmacology and Therapeutic Potential”, DN&P, 10(8), pp. 462-469 (1997).
International Search Report for PCT/US2005/007987 filed Mar. 10, 2005.
Naito et al., “Selective Muscarinic Antagonist. II.1)Synthesis and Antimuscarinic Properties of Biphenylylcarbamate Derivatives”, Chem. Pharm. Bull. , vol. 46, No. 8, pp. 1286-1294 (1998).
Wikepedia “Muscarinic receptors” Jun. 2008.
Zlotos et al., “Muscarinic receptor agonists and antagonists”, Exp. Opin. Ther. Patents, 9(8), pp. 1029-1053 (1999).
Ji Yu-Hua
Malathong Viengkham
Mammen Mathai
Mu YongQi
Desai Rita J
Eberle Shelley
Hagenah Jeffrey A.
Theravance Inc.
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