Biphasic crystalline separation of water insoluble orange pigmen

Details Biphasic crystalline separation of water insoluble orange pigmen Biphasic crystalline separation of water insoluble orange pigmen

1992-09-21

1994-06-07

Marx, Irene

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

435118, 435119, 435134, 435911, 4352568, C12P 1700, C12N 114

Patent

active

053189027

ABSTRACT:
Several classes of water immiscible lipophilic phases effect the transfer of crystalline orange precursor pigments produced by Monascus species in an aqueous culture medium from the aqueous to the lipophilic phase without solubilizing a major portion of the pigment. Liquid vegetable and mineral oils are two such classes. This phenomenon permits high recovery of pigment in a simple and convenient manner, and also permits development of a batch recycle and a continuous fermentation process for pigment production.

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Kumasaki et al., Tetrahedron, 18, 1171 (1962).
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