Biotinylated chemiluminescent labels and their conjugates, assay

Details Biotinylated chemiluminescent labels and their conjugates, assay Biotinylated chemiluminescent labels and their conjugates, assay

1992-08-21

1995-03-07

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

5483037, 5483041, 530408, 530409, 436501, 435 75, C07D49504

Patent

active

053959388

ABSTRACT:
A unique class of chemiluminescent labels containing biotin substitution that are suitable for chemiluminescent assays using inter alia a streptavidin and/or avidin conjugate. The chemiluminescent labels of the invention have the ability to bind to streptavidin and/or avidin per se or to streptavidin and/or avidin conjugated with an analyte. Label structures are disclosed that have hydrolytic stability to meet the most demanding commercial assay conditions. The invention encompasses conjugates containing associated versions of the labeling compounds, assays and kits for performing such assay utilizing the conjugates.

REFERENCES:
patent: 5162352 (1992-11-01), Hall et al.
patent: 5180828 (1993-01-01), Ghazarossian et al.

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