Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is inorganic
Patent
1996-12-31
1998-12-22
Ceperley, Mary E.
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is inorganic
128899, 424423, 436500, 436527, 436806, 436823, 5483041, 558419, G01N 33553, C07D49504
Patent
active
058518401
ABSTRACT:
The invention concerns a binding matrix containing a carrier material with an oxidic surface and a solid phase reactant covalently bound thereto via anchor groups which is capable of binding to at least one free reaction partner, which is characterized in that the solid phase reactant forms a diluted and essentially laterally homogeneous binding layer on the surface of the carrier material and that the anchor groups are silane groups and are linked to the solid phase reactant via a spacer molecule.
REFERENCES:
patent: 4081245 (1978-03-01), Polito
patent: 4128629 (1978-12-01), Eldred et al.
patent: 4410633 (1983-10-01), Hertl et al.
patent: 4833093 (1989-05-01), Malmqvist et al.
patent: 5240602 (1993-08-01), Hammen
patent: 5405766 (1995-04-01), Kallury et al.
Analytical Letter, 23(3), 411-424, 1990, Dr. L. Angermaier A Novel Instrumental Set-Up for In-Situ Detection of Protein Adsorption With Grating Coupler Sensors (GCS).
Biophysical Jrl., vol. 60, Sep. 1991, R. Barner et al., Direct Optical Immuno Sensors (Sensivity and Selectivity).
Analytical Bio. 145, 106-112, (1985), Hans Arwin et al., A Reflectance Method For Quantification of Immunological Reactions on Surfaces.
Science, vol. 252, May 1991, Kevin Prime et al., Self-Assembled Organic Monolayers: Model Systems For Studying Adsorption of Proteins at Surfaces.
Colloids and Surfaces B: Biointerfaces I (1993) 107-117, P.W. Wojciechowski et al., Fibrinogen and Albumin Adsorption from Human Blood Plasma and From Buffer onto Chemically Functionalized Silica Substrates.
Fed. Pro vol. 30, No. May 10, 1971, Vincent L. Gott, et al., Antithrombogenic Surfaces, Classification and in Vivao Evaluation on Surfaces.
Vol. XXVI, Trans. Am. Soc. Artif. Intern Organs 1980, H. Bayer et al., Properties of Porous Glass Membranes With Respect to Application In Blood Purification.
Pharmazeutische Technologie, pp. 169-175.
Tetrahedron Letters, 32(14), 1715-18 (1991), Richard T. Pon "A Long Chain Biotin Phosphoramidite Reagent For the Automated Synthesis of 5'-Biotinylated Oligonucleotides".
Batz Hans-Georg
Sluka Peter
Boehringer Mannheim GmbH
Ceperley Mary E.
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