Biotechnological process for the preparation of cyclic s-alpha-i

Details Biotechnological process for the preparation of cyclic s-alpha-i Biotechnological process for the preparation of cyclic s-alpha-i

1996-03-12

1998-06-16

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

435122, 435128, 435874, 435876, 435877, C12P 1710, C12P 1712, C12P 1300, C12N 120

Patent

active

057668930

ABSTRACT:
Microorganisms of interest are capable of utilizing .alpha.-imino carboxamides, in the form of the racemate or of its optically active isomers, of the general formula ##STR1## wherein A together with --NH-- and --CH-- is an optionally substituted 5- or 6-membered saturated heterocyclic ring, as sole nitrogen source, and converting (RS)-.alpha.-imino carboxamides of Formula I into an S-.alpha.-imino carboxylic acid of the general formula ##STR2## These microorganisms are useful also for biconversion of an (RS)-.alpha.-imino carboxamide of Formula I into an S-.alpha.-imino carboxylic acid.

REFERENCES:
Chemical Abstracts, vol. 110, No. 11, Mar. 13, 1989, Abstract No. 93556p.
Chemical Abstracts, vol. 112, No. 15, Apr. 9, 1990, Abstract No. 137533b. J. Org. Chem., 1994, vol. 59, pp. 2075-2081. Biosci. Biotech. Biochem., 1992, vol. 56, pp. 2081-2082. and Bioenginering, 1992, vol. 74, pp. 189-190.

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