Biosynthetic pathway and genes required for tropodithietic...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S023700, C435S189000, C435S193000, C435S196000

Reexamination Certificate

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08058417

ABSTRACT:
Production and use of a sulfur-containing compound, tropodithietic acid (TDA), from theroseobacter Silicibactersp. TM1040 is described. Specifically, a biosynthetic and regulatory pathway for TDA biosynthesis inroseobactersis described. The TDA produced fromroseobacters, specificallySilicibactersp. TM1040, is shown to have antibacterial activity, in particular againstVibrio anguillarium, Vibrio cholerae, Vibrio coralliilyticus, Vibrio shiloi, Halomonasspp.,Mycobacterium marinum, Mycobacterium tuberculosis, Pseudomonas elongate, Spongiobacter nikelotolerans, andStaphylococcus aureus(MRSA).

REFERENCES:
patent: 2004/0175407 (2004-09-01), MacDaniel
patent: 2006/0257961 (2006-11-01), Apicella et al.
patent: 2009/0142429 (2009-06-01), Belas et al.
patent: 2006127823 (2006-11-01), None
Belas,R., et al., Mar. 13, 2007, GenEmbl Accession No. EF139204, “Mutant Silicibacter sp. TM1040 Acyl-CoA dehydrogenase (tdaE) gene, complete sequence”, Length = 1701nt.
Belas,R., et al., Mar. 13, 2007, GenEmbl Accession No. EF139205, “Mutant Silicibacter sp. TM1040 phosphopantothenoylcysteine decarboxylase (tdaF) gene, complete sequence”, Length = 672nt.
Miller, Todd R., et al., “Chemotaxis of Silibacter sp. Strain TM1040 toward Dinoflagellate Products”, “Appl. Environ. Microbiol.”, Aug. 2004, pp. 4692-4701, vol. 70, No. 8.
Bourne, David G., et al., “Diversity of bacteria associated with the coral Pocillopora damicornis from the Great Barrier Reef”, “Environ. Microbiol.”, Aug. 2005, pp. 1162-1174, vol. 7, No. 8.
Brinkhoff, Thorsten, et al., “Antibiotic Production by a Roseobacter Clade-Affiliated Species from the German Wadden Sea and Its Antagonistic Effects”, “Appl. Environ. Microbiol.”, Apr. 2004, pp. 2560-2565, vol. 70, No. 4.
Bruhn, Jesper Bartholin, et al., “Ecology, Inhibitory Activity, and Morphogenesis of a Marine Antagonistic Bacterium Belonging to the Roseobacter Clade”, “Appl. Environ. Microbiol.”, Nov. 2005, pp. 7263-7270, vol. 71, No. 11.
Christie, Peter J., et al., “Bacterial type IV secretion: conjugation systems adapted to deliver effector molecules to host cells”, “Trends Microbiol.”, Aug. 2000, pp. 354-360, vol. 8, No. 8.
Miller, Todd R., et al., “Dimethylsulfoniopropionate Metabolism by Pfiesteria-Associated Roseobacter spp.”, “Appl. Environ. Microbiol.”, Jun. 2004, pp. 3383-3391, vol. 70, No. 6.
Ruiz-Ponte, C., et al., “The Benefit of a Roseobacter Species on the Survival of Scallop Larvae”, “Mar. Biotechnol.”, Jan. 1999, pp. 52-59, vol. 1, No. 1.
Chen, Feng, et al., “Induction of Multiple Prophages from a Marine Bacterium: a Genomic Approach”, “Applied and Environmental Microbiology”, 2006, pp. 4995-5001, vol. 72, No. 7.
Galperin, Michael Y., “Sampling of microbial diversity by complete genomes”, “Environmental Microbiology”, 2006, pp. 1313-1317, vol. 8, No. 8.
Moran, Mary Ann, et al., “Genome sequence of Silicibacter pomeroyi reveals adaptations to the marine environment”, “Nature”, 2004, pp. 910-913, vol. 432, No. 7019.
Moran, M.A., et al., “Ecological Genomics of Marine Roseobacters”, “Applied and Environmental Microbiology”, 2007, pp. 4559-4569, vol. 73, No. 14.

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