Biosynthetic gene murg from streptococcus pneumoniae

Details Biosynthetic gene murg from streptococcus pneumoniae Biosynthetic gene murg from streptococcus pneumoniae

1996-11-19

1998-10-13

Hutzell, Paula K.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530300, 5303884, 435 71, 435 734, 435 15, 435 32, 435 36, 435 691, 4242341, 4242441, C07K 14315, G01N 3353, A61K 3909

Patent

active

058213350

ABSTRACT:
The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene murG of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurG enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.

REFERENCES:
patent: 5501957 (1996-03-01), Denny et al.
patent: 5525616 (1996-06-01), Platt et al.
Dominique Mengin-Lecreulx, et al., Journal of Bacteriology, Aug. 1991, pp. 4625-2636.

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