Biosynthesis of simplified anthracyclines

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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4351721, 435886, C12P 1956, C12N 1500, C12R 1465

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active

044710526

ABSTRACT:
Chemically simplified versions of intermediates on the identified biosynthetic pathway to daunomycin are bioconverted to active analogues of naturally occurring antibiotics.

REFERENCES:
patent: 3590028 (1971-06-01), Arcamone et al.
patent: 4267312 (1981-05-01), Oki et al.
patent: 4309503 (1982-01-01), Cassinelli et al.
patent: 4337312 (1982-06-01), Oki et al.
Oki et al., J. Antibiotics, 33(11): 1331-1340 (1980).
Yoshimoto et al., J. Antibiotics, 33(10): 1199-1201, 1158-1166 (1980).

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