Biosynthesis of phloroglucinol and preparation of...

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S320100, C435S252330, C435S252340, C435S183000, C435S069100, C435S156000, C435S254200, C435S254110, C536S023200

Reexamination Certificate

active

07943362

ABSTRACT:
The present invention provides methods, enzymes, and cells for the biosynthetic production of phloroglucinol from malonyl-CoA, which is ultimately obtained from simple starting materials such as glucose; also provided are methods for preparing derivatives of biosynthetic phloroglucinol, including, e.g., resorcinol.

REFERENCES:
patent: 4760048 (1988-07-01), Kurihara et al.
patent: 5350576 (1994-09-01), Payne et al.
patent: 6051383 (2000-04-01), Thomashow et al.
patent: 6194167 (2001-02-01), Browse et al.
patent: 6322820 (2001-11-01), Simoneau
patent: 6767744 (2004-07-01), Koffas et al.
patent: 6774107 (2004-08-01), Strittmatter et al.
patent: 6783758 (2004-08-01), Wands et al.
patent: 6790639 (2004-09-01), Brown et al.
patent: 1 182 205 (1970-02-01), None
patent: 1 278 576 (1972-06-01), None
patent: 1 509 358 (1978-05-01), None
patent: 99/26479 (1999-06-01), None
patent: 00/71110 (2000-11-01), None
patent: 2006/044290 (2006-04-01), None
Branden et al., Introduction to Protein Structure, Garland Publishing Inc., New York, p. 247, 1991.
Witkowski et al., Biochemistry 38:11643-11650, 1999.
Seffernick et al., J. Bacteriol. 183(8):2405-2410, 2001.
The 1998 INVITROGEN catalog, p. 12.
Abbas, A., et al., J. Bacteriol., vol. 184, p. 3008 (2002).
Abbas, A., et al., Microbiology, vol. 150, p. 2443 (2004).
Achkar, Jihane et al., “Biosynthesis of phloroglucinol,” Journal of the American Chemical Society, vol. 127, No. 15, pp. 5332-5333 (Apr. 2005).
Agatep, R., et al., Technical Tips Online, vol. 1, p. 01525 (1998).
Austin, M.B., et al., Nat. Prod. Rep., vol. 20, p. 79-110 (2003).
Bangera M Gita, et al., “Identification and characterization of a gene cluster for synthesis of the polyketide antibiotic 2, 4-diacetylphloroglucinol fromPseudomonas fluorescensQ2-87,” Journal of Bacteriology, vol. 181, No. 10, pp. 3155-3163 (May 1999).
Baas, D. et al., Eur. J. Biochem., vol. 265, pp. 896-901 (1999).
Beck, J., et al., Eur. J. Biochem, vol. 192, p. 487 (1990).
Brown, N.P., et al., Bioinformatics: Application Note, vol. 14, pp. 380-381 (1998).
Chen, et al., Biochemistry, vol. 29, p. 1112 (1990).
Davis, M.S., et al., J. Biol. Chem., vol. 275, p. 28593 (2000).
Delany, I., et al., Microbiol. vol. 146, p. 537 (2000).
Draths, K.D., et al., J. Am. Chem. Soc., vol. 117, p. 2395 (1995).
Eckermann, S., et al., Nature, vol. 396, p. 387 (1998).
Gibson, J., et al., Angew. Chem., Int. Ed., vol. 40, p. 1945 (2001).
Hansen, Chad A. et al., “Deoxygenation of plyhydroxybenzenes: an alternative strategy for the benzene-free synthesis of aromatic chemicals,” Journal of the American Chemical Society, vol. 124, No. 21, pp. 5926-5927 (May 2002).
Hansen, Chad A., “Chemo-Enzymatic Synthesis of Aromatics via Non-Shikmate Pathway Intmediates,” PhD Thesis Chapter 3-4. Michigan State University (2002).
Jez, J.M., et al., Chem. Bio., vol. 7, pp. 919-930 (2000).
Kambourakis, et al., J. Am. Chem. Soc., vol. 122, p. 9042 (2000).
Krumenacker, L., et al., Kirk-Othmer Encyclopedia of Chemical Technology, J.I. Kroschwitz & M. Howe-Grant, eds., vol. 13, p. 996 (4thed., 1995).
Ma, H., et al., Gene., vol. 58, pp. 201-216 (1987).
Meurer, G., et al., Mol. Gen. Genet., vol. 232, 106-116, 1992.
Mumberg, D., et al., Gene., vol. 156, pp. 119-122, 1995.
Novak-Thompson, B., et al., Can. J. Microbiol., vol. 40, p. 1064, (1994).
Paulsen, Ian T. et al., “Complete genome sequence of the plant commensalPseudomonas fluorescensPf-5,” Nature Biotechnology, vol. 23, No. 7, pp. 873-878 (Jul. 2005).
Pichuantes, S., et al., In Protein engineering: Principles and Practice; Cleland, J.L.; Craik, C.S., Eds.; Wiley-Liss, Chapter 5, pp. 129-161 (1996).
Ramette, A., et al., Plant-Microbe Interact, vol. 14, p. 639 (2001).
Ran, N., et al., J. Am. Chem. Soc., vol. 123, p. 10927, (2001).
Rescigno, M., et al., Biochemistry, vol. 33, p. 5721 (1994).
Reid, et al., “A model of structure and catalysis for ketoreductase domain in modular polyketide synthases,” Biochemistry, vol. 42, pp. 72-79 (2003).
Richardson, et al., Metab. Eng., vol. 1, p. 180 (1999).
Romanos, M.A., et al., Yeast., vol. 8, pp. 423-488 (1992).
Schnider-Keel, U., et al., J. Bacteriol., vol. 182, p. 1215 (2000).
Schoefer, L. et al., Appl. Environ. Microbiol., vol. 70, No. 10, pp. 6131-6137 (2004).
Schorr, et al., J. Plant Physiol. vol. 143, p. 407 (1994).
Shanahan, P., et al., Anal. Chim. Acta, vol. 272, p. 271 (1993).
Spencer, et al., Biochem J., vol. 288, p. 839 (1992).
Takamura, et al., J. General Microbiol., vol. 134, p. 2249 (1988).
Vadali, R.V., et al., Metab. Eng., vol. 6, pp. 133-139 (2004).
Vallari, D.S., et al., J. Biol. Chem., vol. 262, p. 2468 (1987).
Zha, Wenjuan, et al., “Rational pathway engineering of type I fatty acid synthase allows the biosynthese of triacetic acid lactone from D-glucose in vivo,” J. American Chemical Society, vol. 126, No. 14, pp. 4534-4535, (Apr. 2004).
Database Embl. (Online), “Pseudomonas fluorescensphID gene for PhID, complete cds.,”, Database accession No. AB125213 (Oct. 30, 2003).
Database Embl. (Online), “Pseudomonas fluorescensstrain Pf5 putative polyketide synthase PhID (phID) gene, partial cds.,”, Database accession No. AF214457 (Dec. 29, 1999).
Database Embl. (Online), “Pseudomonas fluorescens2,4-diacetylphloroglucinol biosynthesis genes: Ph1E (ph1E), Ph1D (ph1D), Pg1B (ph1B), Ph1C (ph1C), Ph1A (ph1A), Ph1F (ph1F) genes, complete cds.,”, Database accession No. U41818 (Jan. 26, 1996).
International Search Report for International App. No. PCT/US2005/036291 (6 pages), Sep. 22, 2006.
International Preliminary Report on Patentability for International App. No. PCT/US2005/036291 (8 pages), Feb. 19, 2007.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Biosynthesis of phloroglucinol and preparation of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Biosynthesis of phloroglucinol and preparation of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biosynthesis of phloroglucinol and preparation of... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2679919

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.