Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Patent
1989-04-28
1990-01-30
Lilling, Herbert J.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
435170, 435802, 435818, 435885, C12P 1904, C12R 146
Patent
active
048973491
ABSTRACT:
Improved overall yields of hyaluronic acid are obtained by controlling the oxygen available for metabolism by a hyaluronic acid producing microorganism. Relatively high oxygen concentrations are made available during the initial exponential growth phase of the cultivated microorganism, until a predetermined growth has been reached. At this time, the available oxygen is limited to stimulate a disproportionately larger production of the desired hyaluronic acid.
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Jamieson Gordon
Richardson Kenneth R.
Singh Tarlach
Sullivan Bernard P.
Swann David A.
Lilling Herbert J.
MedChem Products, Inc.
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