Biostable corneal implants

Details Biostable corneal implants Biostable corneal implants

1996-03-15

1997-05-27

Prebilic, Paul B.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Eye prosthesis

Corneal implant

623 6, 523105, 523108, A61F 214

Patent

active

056327730

ABSTRACT:
Corneal implants and methods for producing such implants are disclosed. The present corneal implants comprise a lens body which is optically clear and is structured to be surgically attached in or on the cornea of a mammalian eye, the lens body including a hydrogel composition containing water, a collagen component and a polymeric material covalently bonded to the collagen component. The hydrogel composition has enhanced biostability relative to an identical hydrogel composition without the polymeric material.

REFERENCES:
patent: 4388428 (1983-06-01), Kuzma et al.
patent: 4589964 (1986-05-01), Mayhan et al.
patent: 4806382 (1989-02-01), Goldberg et al.
patent: 4845132 (1989-07-01), Masuoka et al.
patent: 4919659 (1990-04-01), Horbett et al.
patent: 4961954 (1990-10-01), Goldberg et al.
patent: 4983181 (1991-01-01), Civerchia
patent: 5002582 (1991-03-01), Guire et al.
patent: 5112350 (1992-05-01), Civerchia et al.
patent: 5192316 (1993-03-01), Ting
patent: 5201764 (1993-04-01), Kelman et al.
patent: 5433745 (1995-07-01), Graham et al.
Hino et al, A Study on Collagen-Plastic Composites as Biomaterials, "Biocompatability of Tissue Analogs", vol. II, pp. 71-87.
Suzuki et al, Graft Copolymerization of Acrylamide onto a Polyethylene Surface Pretreated with a Glow Discharge, Macromolecules 1986, 1804-1808.
Yeh et al, Blood compatibility of surface modified by plasma polymerization, Journal of Biomedical Materials Research, vol. 22, 795-818 (1988).
Petit et al, Quanitation of Rabbit Corneal Epithelial Cell Outgrowth on Polymeric Substrates in Vitro, "Investigative Opthalmology & Visual Science,"vol. 31, No. 11, Nov. 1990.
Horbett et al, Hydrophilic-Hydrophobic Copolymers as Cell Substrates: Effect on 3T3 Cell Growth Rates, Journal of Colloid and Interface Science, vol. 104, No. 1, Mar. 1985.
Dreyfuss et al, Graft Polymers, vol. 7, pp. 551-579 Encyclopedia of Polymer Science and Engineering.
Gombotz et al, Gas-Discharge Techniques for Biomaterial Modification, vol. 4, Issue 1 (1987) pp. 1-42, "Critical Reviews in Biocompatibility".
Lydon et al, Cellular interactions with synthetic polymer surfaces in culture, Biomaterials 1985, vol. 6 Nov., pp. 396-402.
Kaplan et al, Medical Polymers and Plasma Technology, Technical Notes, Plasma Science, Foster City, California pp. 1-5.
On The Surface, vol. II, No. I, Improved Biocompatibility by Surface Modification, Metro-Line Industries, Inc. Corona, California.
Special Report, Using Gas Plasma to Reengineer Surfaces, Nancy B. Mateo, Reprinted from Medical Product Manufacturing News, Sep./Oct. 1990 pp. 1-2.
Dekker et al, Adhesion of endothelial cells and adsorption of serum proteins of gas plasma-treated polytetrafluoro-ethylene, Biomaterials 1991, vol. 12 Mar., pp. 130-138.
H. Boenig, Plasma Polymerization, vol. 11, pp. 249-261, Academic Press, Inc., Orlando, Fla, 1986 Encyclopedia of Polymer Science and Engineering.
Ratner et al, Plasma Deposition and Treated for Biomaterial Applications "Plasma Deposition of Polymer Films", Academic Press, Boston, 1989.

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