Biosensors having enhanced environmental sensitivity

Optical waveguides – Optical waveguide sensor

Reexamination Certificate

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C385S039000, C385S123000

Reexamination Certificate

active

07010182

ABSTRACT:
A biosensor having enhanced sensitivity to physical or chemical parameters comprises a waveguide and a coating disposed on the waveguide. The coating has a refractive index that enhances the sensitivity of the biosensor to physical or chemical parameters. In a preferred embodiment, the coating comprises at least one dendrimer disposed on the waveguide, wherein the coating has a refractive index ranging from about 1.0 to about 1.5. A method for fabrication of the biosensor is also provided.

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Petar R. Dvornic, Agnes De Leuze-Jallouli, Michael J. Owne, and Susan V. Perez, “Nanostructured Films, Coatings, molecular “Sponges” and “Reactors” from Copolymeric Amidoamine-Organosilicon (PAMAMOS) Dendrimers,” Polymer Preprints, 1999, vol. 40, pp. 408-409.

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