Biosensor system having enhanced stability and hematocrit...

Details Biosensor system having enhanced stability and hematocrit... Biosensor system having enhanced stability and hematocrit...

2011-01-04

2011-01-04

Neckel, Alexa D (Department: 1795)

Chemistry: electrical and wave energy

Apparatus

Electrolytic

C205S787000, C435S817000, C435S014000, C204S403090, C422S082010

Reexamination Certificate

active

07862696

ABSTRACT:
The present invention relates to electrochemical sensor strips and methods of determining the concentration of an analyte in a sample or improving the performance of a concentration determination. The electrochemical sensor strips may include at most 8 μg/mm2of a mediator. The strips, the strip reagent layer, or the methods may provide for the determination of a concentration value having at least one of a stability bias of less than ±10% after storage at 50° C. for 4 weeks when compared to a comparison strip stored at −20° C. for 4 weeks, a hematocrit bias of less than ±10% for whole blood samples including from 20 to 60% hematocrit, and an intercept to slope ratio of at most 20 mg/dL. A method of increasing the performance of a quantitative analyte determination also is provided.

REFERENCES:
patent: 3791933 (1974-02-01), Wenz et al.
patent: 3791988 (1974-02-01), Bauer et al.
patent: 4711245 (1987-12-01), Higgins et al.
patent: 4746607 (1988-05-01), Mura et al.
patent: 5108564 (1992-04-01), Szuminsky et al.
patent: 5120420 (1992-06-01), Nankai et al.
patent: 5128015 (1992-07-01), Szuminsky et al.
patent: 5206147 (1993-04-01), Hoenes
patent: 5262035 (1993-11-01), Gregg et al.
patent: 5264104 (1993-11-01), Gregg et al.
patent: 5288387 (1994-02-01), Pollmann et al.
patent: 5288636 (1994-02-01), Pollmann et al.
patent: 5320725 (1994-06-01), Gregg et al.
patent: 5356786 (1994-10-01), Heller et al.
patent: 5393615 (1995-02-01), Cory et al.
patent: 5498542 (1996-03-01), Cory et al.
patent: 5520786 (1996-05-01), Bloczynski et al.
patent: 5545519 (1996-08-01), Vadagama et al.
patent: 5582697 (1996-12-01), Ikeda et al.
patent: 5620579 (1997-04-01), Genshaw et al.
patent: 5628890 (1997-05-01), Carter et al.
patent: 5631371 (1997-05-01), Bloczynski
patent: 5631863 (1997-05-01), Fechner et al.
patent: 5653863 (1997-08-01), Genshaw et al.
patent: 5682884 (1997-11-01), Hill et al.
patent: 5695947 (1997-12-01), Guo et al.
patent: 5708247 (1998-01-01), McAleer et al.
patent: 5762770 (1998-06-01), Pritchard et al.
patent: 5798031 (1998-08-01), Charlton et al.
patent: 5820551 (1998-10-01), Hill et al.
patent: RE36268 (1999-08-01), Szuminsky et al.
patent: 5951836 (1999-09-01), McAleer et al.
patent: 5958199 (1999-09-01), Miyamto et al.
patent: 5997817 (1999-12-01), Crismore et al.
patent: 6153069 (2000-11-01), Pottgen et al.
patent: 6258229 (2001-07-01), Winarta et al.
patent: 6284125 (2001-09-01), Hodges et al.
patent: 6287451 (2001-09-01), Winarta et al.
patent: 6297697 (2001-10-01), Delano et al.
patent: 6413398 (2002-07-01), Gerhardt et al.
patent: 6413411 (2002-07-01), Pottgen et al.
patent: 6475372 (2002-11-01), Ohara et al.
patent: 6484046 (2002-11-01), Say et al.
patent: 6911131 (2005-06-01), Miyazaki et al.
patent: 2001/0006149 (2001-07-01), Taniike et al.
patent: 2005/0016844 (2005-01-01), Burke et al.
patent: 0330517 (1989-02-01), None
patent: 0354441 (1990-02-01), None
patent: 1074832 (2001-02-01), None
patent: 1691192 (2004-03-01), None
patent: 1707953 (2006-04-01), None
patent: 1742045 (2007-01-01), None
patent: WO 8803270 (1988-05-01), None
patent: WO 2005040407 (2005-05-01), None
patent: WO 2006042304 (2006-04-01), None
patent: WO 2006096619 (2006-09-01), None
EPO, “Search Report and Written Opinion for PCT/US2007/077955”, Dec. 18, 2007, Publisher: International Searching Authority.
A.D. Smith, Ed., “Oxford Dictionary od Biochemistry and Molecular Biology, Revised Edition”, 2000, pp. 161,476,477,560, Publisher: Oxford University Press.
Ho et, al., “Electrochemical Sensor for Measurements of Urea and Creatinine in Serum Based on ac impedance Measurment of Enzyme-Catal”, 1999, pp. 1940-1946, vol. 71, Publisher: Anal. Chem.
Razumiene et, al., “Improvement of screen-printed carbon electrodes by modifications with ferreocene derivative”, “Sensors and Actuators B, Elesvier Sequioa”, 2003, pp. 378-383, vol. 95, No. 1-3.
Fultz, et al., “Mediator Compounds for the Electrochemical Study of Biological Redox System: A Compilation”, 1982, pp. 1-18, vol. 140, Publisher: Analytica Chimica Acta.

Affiliated with

Also associated with

Rating

Biosensor system having enhanced stability and hematocrit... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Biosensor system having enhanced stability and hematocrit..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biosensor system having enhanced stability and hematocrit... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2721746