Biosensor

Details Biosensor Biosensor

1996-04-08

1999-04-06

Brock, Michael

Measuring and testing

Liquid analysis or analysis of the suspension of solids in a...

Gelling or coagulation

73 5925, G01N 2900

Patent

active

058921443

ABSTRACT:
A biosensor (10) for measuring changes in viscosity, density and/or mass in a fluid to be examined, for example a blood coagulation sensor or immunoassay system. According to the invention, the reagents necessary for the test are contained in a support (13) which is put onto the measurement surface (18) of a piezoelectric element (8). As a blood coagulation sensor, the measurement surface (18) may according to the invention itself have a coagulation activator action or else be coated with coagulation activators.

REFERENCES:
patent: 4236893 (1980-12-01), Rice
patent: 4695956 (1987-09-01), LeVeen et al.
patent: 4735906 (1988-04-01), Bastiaans
patent: 4849340 (1989-07-01), Oberhardt
patent: 5211054 (1993-05-01), Muramatsu et al.
patent: 5494639 (1996-02-01), Grzegorzewski
Muramatsu et al., "A Quartz Crystal Viscosity Sensor For Monitoring Coagulation Reaction and its Application to a Multichannel Coagulation Detector", Biosensors & Bioeelectronics, 6:353-358 (1991).
Muratsugu et al., "Detection of Antistreptolysin O Antibody: Application of an Initial Rate Method of Latex Piezoelectric Immunoassay", Anal. Chem., 64(21) :2483-2487 (1992).
Shana et al., "Quartz Crystal Resonators as Sensors in Liquids Using the Acoustoelectric Effect", Anal. Chem., 66 (13) :1955-1964 (1994).

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