Biosensor

Details Biosensor Biosensor

2005-12-20

2005-12-20

Chin, Christopher L. (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

C204S400000, C204S403060, C422S082010, C422S082020, C422S082030, C435S005000, C435S006120, C435S007200, C435S007310, C435S014000, C435S287100, C435S287200, C436S149000, C436S524000, C436S525000, C436S806000, C436S815000

Reexamination Certificate

active

06977180

ABSTRACT:
The present invention relates, in general, to biosensors and, in particular, to bioelectronic sensors comprising a macromolecule immobilized on an electrode surface so that a redox cofactor that is site-specifically attached to the surface of the macromolecule is between the macromolecule and electrode surface ligand-mediated conformational changes alter the geometry of interaction between the redox cofactor and the electrode surface resulting in a change in electronic coupling between the cofactor and electrode.

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