Bioresorbable nerve guide rail

Details Bioresorbable nerve guide rail Bioresorbable nerve guide rail

2007-04-03

2007-04-03

Weber, Jon (Department: 1652)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C623S023640, C623S023750, C528S272000

Reexamination Certificate

active

11149122

ABSTRACT:
A biologically resorbable nerve guide rail with a microporous guide tube of polymers of hydroxycarboxylic acids, where the porosity allows a metabolism through the tube wall, but prevents the passage of cells, and optionally several monofilaments of polymers of hydroxycarboxylic acids located in the guide tube, is characterized in that the inner surface of the tube and/or the surface of the monofilaments have an orientation aid for longitudinally oriented colonization with Schwann's cells.

REFERENCES:
patent: 4617271 (1986-10-01), Nambu
patent: 5358475 (1994-10-01), Mares et al.
patent: 5656605 (1997-08-01), Hansson et al.
patent: 5834029 (1998-11-01), Bellamkonda et al.
patent: 5908783 (1999-06-01), Brewer
patent: 5925053 (1999-07-01), Hadlock et al.
patent: 6090117 (2000-07-01), Shimizu
patent: 6676675 (2004-01-01), Mallapragada et al.
patent: 33 23 430 (1985-01-01), None
patent: 41 08 772 (1992-09-01), None
patent: 689 22 319 (1996-01-01), None
patent: 196 41 334 (1998-04-01), None
patent: 197 36 449 (1999-02-01), None
patent: 04-262780 (1992-09-01), None
patent: 04262780 (1992-09-01), None
patent: 04322657 (1992-11-01), None
patent: 04322657 (1992-11-01), None
Steuer et al., “Biohybride nerve guide for regeneration: degradable polylactide fibers coated with Schwann cells,” Neurosci Lett 277:165-168, 1999.
Molecular Cell biology 4th Ed., Lodish et al., eds., W. H. Freeman & Co., New York, 2000, pp. 912, 913 and 925.
Steuer, H., et al., “Biohybride nerve guide for regeneration degradable polyactide fibers coated with rat Schwann cells.” Neuroscience Letter, vol. 277, pp. 165-168, 1999.
Johnson, Alan R., “Contact Inhibition in the Failure of Mammalian CNS Axonal Regeneration.” BioEssays, vol. 15, No. 12, pp. 807-813, Dec. 1993.
Dodd, Jane, et al., “Axon Guidance: A Compelling Case for Repelling Growth Cones.” Cell, vol. 81, pp. 471-474, May 19, 1995.
Kolodkin, Alex K., “Growth cones and the cues that repel them.” Trends Neurosci., vol. 19, pp. 507-513, 1996.

Affiliated with

Also associated with

Rating

Bioresorbable nerve guide rail does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Bioresorbable nerve guide rail, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bioresorbable nerve guide rail will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3741204