Bioresorbable hydrogel compositions for implantable prostheses

Details Bioresorbable hydrogel compositions for implantable prostheses Bioresorbable hydrogel compositions for implantable prostheses

2006-09-19

2008-10-28

Nutter, Nathan M (Department: 1796)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C424S424000, C424S426000, C623S001150, C623S001420, C623S001490

Reexamination Certificate

active

07442384

ABSTRACT:
Crosslinked compositions formed from water-insoluble copolymers are disclosed. These compositions are copolymers having a bioresorbable region, a hydrophilic region and at least two cross-linkable functional groups per polymer chain. Crosslinking of these polymers can be effected in solution in organic solvents or in solvent-free systems. If crosslinking occurs in a humid environment, a hydrogel will form. If crosslinking occurs in a non-humid environment, a xerogel will form which will form a hydrogel when exposed to a humid environment and the resulting crosslinked materials form hydrogels when exposed to humid environments. These hydrogels are useful as components in medical devices such as implantable prostheses. In addition, such hydrogels are useful as delivery vehicles for therapeutic agents and as scaffolding for tissue engineering applications.

REFERENCES:
patent: 5411550 (1995-05-01), Herweck et al.
patent: 5981566 (1999-11-01), Wernthaler et al.
patent: 2002/0133183 (2002-09-01), Lentz et al.

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